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	Provedor de dados BJID (1) Genet. Mol. Biol. (1) Autor Ribeiro,José Dirceu (2) Almeida,Renata Servan de (1) Arns,Clarice Weis (1) Baracat,Emílio Carlos Elias (1) Bertuzzo,Carmen Silvia (1) Faria,Isabel Cristina Jacinto (1) Lima,Carmen Silvia Passos (1) Lourenço,Gustavo Jacob (1) Néri,Iramaia Angélica (1) Riccetto,Adriana Gut Lopes (1) Silva,Marcos Tadeu Nolasco da (1) Mais... Palavra-chave Acute respiratory infection (1) Atopic asthma (1) GSTM1 gene (1) GSTT1 gene (1) Pathogenesis (1) Respiratory syncytial virus (1) Risk factors (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2010 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil Genet. Mol. Biol. Lima,Carmen Silvia Passos; Néri,Iramaia Angélica; Lourenço,Gustavo Jacob; Faria,Isabel Cristina Jacinto; Ribeiro,José Dirceu; Bertuzzo,Carmen Silvia. Xenobiotics can trigger degranulation of eosinophils and mast cells. In this process, the cells release several substances leading to bronchial hyperactivity, the main feature of atopic asthma (AA). GSTM1 and GSTT1 genes encode enzymes involved in the inactivation of these compounds. Both genes are polymorphic in humans and have a null variant genotype in which both the gene and corresponding enzyme are absent. An increased risk for disease in individuals with the null GST genotypes is therefore, but this issue is controversial. The aim of this study was to investigate the influence of the GSTM1 and GSTT1 genotypes on the occurrence of AA, as well as on its clinical manifestations. Genomic DNA from 86 patients and 258 controls was analyzed by polymerase... Tipo: Info:eu-repo/semantics/article Palavras-chave: Atopic asthma; Pathogenesis; GSTM1 gene; GSTT1 gene. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000300007 Respiratory syncytial virus (RSV) in infants hospitalized for acute lower respiratory tract disease: incidence and associated risks BJID Riccetto,Adriana Gut Lopes; Ribeiro,José Dirceu; Silva,Marcos Tadeu Nolasco da; Almeida,Renata Servan de; Arns,Clarice Weis; Baracat,Emílio Carlos Elias. Respiratory syncytial virus (RSV) is one of the main causes of acute lower respiratory tract infections worldwide. We examined the incidence and associated risks for RSV infection in infants hospitalized in two university hospitals in the state of São Paulo. We made a prospective cohort study involving 152 infants hospitalized for acute lower respiratory tract infections (ALRTI) in two university hospitals in Campinas, São Paulo, Brazil, between April and September 2004. Clinical and epidemiological data were obtained at admission. RSV was detected by direct immunofluorescence of nasopharyngeal secretions. Factors associated with RSV infection were assessed by calculating the relative risk (RR). The incidence of RSV infection was 17.5%. Risk factors... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute respiratory infection; Respiratory syncytial virus; Risk factors. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000500011 Registros recuperados: 2 Primeira ... 1 ... Última

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