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	Provedor de dados BJID (1) Autor Collares,Tiago (1) Dellagostin,Odir A. (1) Entiauspe,Ludmila Gonçalves (1) Nunes,Emily Montosa (1) Rodrigues,Fernanda Martins (1) Seixas,Fabiana Kömmling (1) Silveira,Mariângela Freitas da (1) Mais... Palavra-chave Cervical cancer (1) Epidemiology (1) HIV infection (1) HPV infection (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2014 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Uncommon non-oncogenic HPV genotypes, TP53 and MDM2 genes polymorphisms in HIV-infected women in Southern Brazil BJID Entiauspe,Ludmila Gonçalves; Seixas,Fabiana Kömmling; Nunes,Emily Montosa; Rodrigues,Fernanda Martins; Dellagostin,Odir A.; Collares,Tiago; Silveira,Mariângela Freitas da. Background:It is believed that Human Papillomavirus (HPV) and Human Immunodeficiency Virus coinfection contributes to increase the risk for cervical intraepithelial injuries. Several factors may contribute to cervical cancer (CC) development, including genetic variants such as TP53and MDM2 gene polymorphisms.Materials and methods:A hundred HIV-infected women were examined for HPV detection and its genotypes, as well as the frequencies of the SNPs Arg72Pro and SNP309 and their associations with CC risk factors. Nested Polymerase Chain Reaction (nPCR) was used for HPV detection and PCR-RFLP for TP53 and MDM2 SNP309 genotyping.Results:HPV DNA was detected in 68% of samples. A higher frequency of low-risk HPV genotypes (66.7%) was observed when compared to... Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV infection; HIV infection; Cervical cancer; Epidemiology. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600643 Registros recuperados: 1 Primeira ... 1 ... Última

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