|
|
|
|
|
| Pietra,Renata Celi Carvalho de Souza; Cruz,Rosana Carvalho; Melo,Carla Nunes; Rodrigues,Lívia Bomfim; Santos,Patrícia Campi; Bretz,Gabriel Pissolati Matos; Soares,Betânia Maria; Sousa,Gerdal Roberto de; Ferreira,Marcus Vinícius Lucas; Cisalpino,Patrícia Silva; Magalhães,Paula Prazeres; Farias,Luiz de Macêdo; Pinotti,Marcos. |
| ABSTRACT Antimicrobial photodynamic therapy (aPDT) involves the association of a photosensitizing agent with a light source with the goal of causing apoptosis or microbial lysing. The use of compounds with natural active principles is gaining prominence throughout the world. Several studies from groups that are linked to the development of innovations in the pharmaceutical market have used natural dyes, such as curcumin, the efficacy of which has been demonstrated in aPDT trials. Difficulties related to physicochemical stability, solubility and cell penetration are some of the challenges associated with this field. The present work aimed to prepare, investigate the characteristics and improve the photodynamic activity of PLGA-based nanoparticles loaded... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Curcumin/study; Nanoparticles/evaluation; PLGA; Antimicrobial photodynamic therapy (aPDT).. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200629 |
| |
|
|
|
