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	Provedor de dados BJMBR (2) Autor Rodrigues,M.A. (2) Braga,H. (1) Cabral,M.A. (1) Drummond-Lage,A.P. (1) Gomes,D.A. (1) Leite,M.F. (1) Nathanson,M.H. (1) Pedrosa,M.S. (1) Santos,F.A.V. (1) Wainstein,A.J.A. (1) Mais... Palavra-chave Biopsy (1) Calcium (1) Gastric carcinoma (1) Nucleus (1) Proliferation (1) Receptor tyrosine kinases (1) Sentinel lymph node (1) Stage (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Nuclear calcium signaling: a cell within a cell BJMBR Rodrigues,M.A.; Gomes,D.A.; Nathanson,M.H.; Leite,M.F.. Calcium (Ca2+) is a versatile second messenger that regulates a wide range of cellular functions. Although it is not established how a single second messenger coordinates diverse effects within a cell, there is increasing evidence that the spatial patterns of Ca2+ signals may determine their specificity. Ca2+ signaling patterns can vary in different regions of the cell and Ca2+ signals in nuclear and cytoplasmic compartments have been reported to occur independently. No general paradigm has been established yet to explain whether, how, or when Ca2+ signals are initiated within the nucleus or their function. Here we highlight that receptor tyrosine kinases rapidly translocate to the nucleus. Ca2+ signals that are induced by growth factors result from... Tipo: Info:eu-repo/semantics/article Palavras-chave: Calcium; Proliferation; Receptor tyrosine kinases; Nucleus. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000100004 Sentinel node biopsy using blue dye and technetium99 in advanced gastric cancer: anatomical drainage and clinical application BJMBR Santos,F.A.V.; Drummond-Lage,A.P.; Rodrigues,M.A.; Cabral,M.A.; Pedrosa,M.S.; Braga,H.; Wainstein,A.J.A.. Lymph node metastases are an independent prognosis factor in gastric carcinoma (GC) patients. Radical lymphadenectomy can improve survival but it can also increase surgical morbidity. As a principle, sentinel node (SN) navigation surgery can avoid unnecessary lymphadenectomy without compromising prognosis. In this pilot study, 24 patients with untreated GC were initially screened for SN navigation surgery, of which 12 were eligible. Five patients had T2 tumors, 5 had T3 tumors and 2 had T1 tumors. In 33% of cases, tumor diameter was greater than 5.0 cm. Three hundred and eighty-seven lymph nodes were excised with a median of 32.3 per patient. The SN navigation surgery was feasible in all patients, with a median of 4.5 SNs per patient. The detection success... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gastric carcinoma; Sentinel lymph node; Biopsy; Stage. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000800701 Registros recuperados: 2 Primeira ... 1 ... Última

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