Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BABT (1) Autor Becker,Ana Cláudia (1) Benetti,Cibele Nabhan (1) Dellagnelo,Viviane Aparecida (1) Pereira,Eduardo Manoel (1) Rodrigues,Patrik Oening (1) Silva,Marcos Antonio Segatto (1) Wagner,Theodoro Marcel (1) Mais... Palavra-chave Anti-inflammatory activity (1) Bioavailability (1) Dexamethasone acetate (1) Solubility (1) Β-cyclodextrin (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2014 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Pharmacodynamic and Pharmacokinetic Studies of β-Cyclodextrin:Dexamethasone Acetate Complexes in Mice BABT Rodrigues,Patrik Oening; Becker,Ana Cláudia; Dellagnelo,Viviane Aparecida; Benetti,Cibele Nabhan; Pereira,Eduardo Manoel; Wagner,Theodoro Marcel; Silva,Marcos Antonio Segatto. The aim of this study was to evaluate the in vivo activity of the anti-inflammatory and analgesic effects of a suspension of the complex composed of dexamethasone acetate (DMA) with β-cyclodextrin in comparison to a suspension of the pure DMA. Solid complexes prepared by different methods were evaluated in pharmacodynamics and pharmacokinetics studies. The pharmacodynamic effect was investigated although the capacity of the inhibited the inflammation. Models of abdominal constriction, carrageenan-induced paw oedema and formalin induced licking were used. The study of the pharmacodynamic comparison of free DMA and products of β-CD:DMA demonstrated no significant difference in the majority of the tests performed. Plasma concentrations of DMA and DMA:β-CD... Tipo: Info:eu-repo/semantics/article Palavras-chave: Solubility; Dexamethasone acetate; Β-cyclodextrin; Bioavailability; Anti-inflammatory activity. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000600887 Registros recuperados: 1 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco