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Pharmacological characterization of venoms obtained from Mexican toxoglossate gastropods on isolated guinea pig ileum J. Venom. Anim. Toxins incl. Trop. Dis.
Rojas,A; Feregrino,A; Ibarra-Alvarado,C; Aguilar,MB; Falcón,A; Heimer de la Cotera,E.
The protein-containing extracts prepared from the venom ducts of Conus austini, Conus spurius and Polystira albida caused a concentration-dependent inhibition of spontaneous contractions in guinea pig ileum. The most potent extract was obtained from P. albida venom ducts (IC50 = 0.11 ± 0.02 µg protein/mL). The three extracts produced a moderate inhibition of contractions elicited by acetylcholine (ACh 1 µM), suggesting the presence of anticholinergic compounds. The contractile response elicited by nicotine (10 µM) was significantly reduced by the extracts prepared from the ducts of C. austini and P. albida, which indicates that the venom produced by these species contains toxins that target neuronal nicotinic receptors. All three extracts significantly...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Conoidea; Conus austini; Conus spurius; Guinea pig ileum; Polystira albida; Turridae.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000300009
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Structure of nematocysts isolated from the fire corals Millepora alcicornis and Millepora complanata (Cnidaria: Hydrozoa) J. Venom. Anim. Toxins incl. Trop. Dis.
García-Arredondo,A; Rojas,A; Iglesias-Prieto,R; Zepeda-Rodriguez,A; Palma-Tirado,L.
Structural characteristics of discharged and undischarged nematocysts from the hydrozoans Millepora alcicornis and Millepora complanata, two fire corals collected in the Mexican Caribbean, were examined using transmission electron, scanning and light microscopy. In this study, we report for the first time images of the nematocysts found in these Mexican Caribbean venomous species. Two types of nematocysts were observed in both species, the more abundant identified as macrobasic mastigophore and the other a stenotele type. Macrobasic mastigophores were present in medium and large size classes while stenoteles appeared in only one size.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hydrocoral; Nematocysts; Microscopy images; Macrobasic mastigophore; Stenotele.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000100014
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