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| Buchaim,Rogério Leone; Andreo,Jesus Carlos; Rodrigues,Antonio de Castro; Buchaim,Daniela Vieira; Roque,Domingos Donizeti; Roque,José Sidney; Rosa Júnior,Geraldo Marco. |
| Extended excessive alcohol use causes changes in bone tissue, thus affecting osteogenesis. The objective of this study was to evaluate if demineralized bone matrix (Gen-ox®) associated with bone morphogenetic protein (Gen-pro®) changes bone neoformation in rats submitted to experimental alcoholism. Forty male rats (Rattus norvegicus) were separated into 2 groups of 20 animals each: Group E1, which received ethyl alcohol at 25% and had the surgical cavity filled in only with blood clot; and Group E2, which received ethyl alcohol at 25% and had the surgical cavity filled in with demineralized bovine cortical bone associated with bone morphogenetic protein. The animals were submitted to a three-week period of gradual adaptation to alcohol, and then continued... |
| Tipo: Journal article |
Palavras-chave: Bone repair; Alcoholism; Xenograft; Bone morphogenetic proteins. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100048 |
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