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	Provedor de dados BJPS (1) Autor Alonso-Castro,Angel Josabad (1) Báez-García,José Eduardo (1) González-García,Gerardo (1) Marcos-Fernández,Angel (1) Orozco-Castellanos,Luis Manuel (1) Rivera-Leyva,Julio Cesar (1) Ruiz-Padilla,Alan Joel (1) Zapata-Morales,Juan Ramón (1) Mais... Palavra-chave Bioresorbable polyurethanes (1) Drug delivery (1) Hydrocortisone (1) Macrodiol. (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Hydrocortisone release from tablets based on bioresorbable poly(ether-ester-urethane)s BJPS Orozco-Castellanos,Luis Manuel; Marcos-Fernández,Angel; Alonso-Castro,Angel Josabad; González-García,Gerardo; Báez-García,José Eduardo; Rivera-Leyva,Julio Cesar; Zapata-Morales,Juan Ramón; Ruiz-Padilla,Alan Joel. Abstract Bioresorbable linear poly(ether-ester-urethane)s with different hydrophilic characteristics were synthesized from triblock copolymers of poly(ε-caprolactone)-poly(ethylene oxide)-poly(ε-caprolactone) (PCL-PEO) as macrodiols, and L-lysine diisocyanate (LDI) or hexamethylenediisocyanate (HDI) were used as the required diisocyanates. Macrodiols were obtained by ring-opening polymerization (ROP) of ε-caprolactone (CL). Polyurethanes were synthesized by the reaction of the triblock copolymers with LDI or HDI in solution using stannous 2-ethylhexanoate as catalyst. Polyurethane tablets were fabricated and investigated as prospective drug delivery systems. The effect of the PEO content on the polymers' performance as drug carriers was evaluated. It was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bioresorbable polyurethanes; Drug delivery; Hydrocortisone; Macrodiol.. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100629 Registros recuperados: 1 Primeira ... 1 ... Última

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