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	Provedor de dados BJMBR (2) Autor Russo,E.M.K. (2) Coifman,R. (1) Dalbosco,I.S. (1) Duarte-de-Oliveira,M.A. (1) Lazaretti-Castro,M. (1) Moisés,R.S. (1) Vieira,J.G.H. (1) Mais... Palavra-chave Bone mineral density (1) Brazilian population (1) First-degree relatives (1) Insulin (1) NIDDM (1) Proinsulin (1) Vitamin D receptor genotype (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 1999 (1) 1997 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Vitamin D receptor alleles and bone mineral density in a normal premenopausal Brazilian female population BJMBR Lazaretti-Castro,M.; Duarte-de-Oliveira,M.A.; Russo,E.M.K.; Vieira,J.G.H.. Studies on the association between vitamin D receptor (VDR) polymorphism and bone mineral density (BMD) in different populations have produced conflicting results probably due to ethnic differences in the populations studied. The Brazilian population is characterized by a very broad genetic background and a high degree of miscegenation. Of an initial group of 164, we studied 127 women from the city of São Paulo, aged 20 to 47 years (median, 31 years), with normal menses, a normal diet and no history of diseases or use of any medication that could alter BMD. VDR genotype was assessed by PCR amplification followed by BsmI digestion of DNA isolated from peripheral leukocytes. BMD was measured using dual energy X-ray absorptiometry (Lunar DPX) at the lumbar... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vitamin D receptor genotype; Bone mineral density; Brazilian population. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800003 Specific insulin and proinsulin in normal glucose tolerant first-degree relatives of NIDDM patients BJMBR Coifman,R.; Dalbosco,I.S.; Russo,E.M.K.; Moisés,R.S.. In order to identify early abnormalities in non-insulin-dependent diabetes mellitus (NIDDM) we determined insulin (using an assay that does not cross-react with proinsulin) and proinsulin concentrations. The proinsulin/insulin ratio was used as an indicator of abnormal ß-cell function. The ratio of the first 30-min increase in insulin to glucose concentrations following the oral glucose tolerance test (OGTT; I30-0/G30-0) was taken as an indicator of insulin secretion. Insulin resistance (R) was evaluated by the homeostasis model assessment (HOMA) method. True insulin and proinsulin were measured during a 75-g OGTT in 35 individuals: 20 with normal glucose tolerance (NGT) and without diabetes among their first-degree relatives (FDR) served as controls, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Insulin; NIDDM; Proinsulin; First-degree relatives. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100010 Registros recuperados: 2 Primeira ... 1 ... Última

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