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ALENCAR,DANIEL B. DE; SILVA,SUZETE R. DA; PIRES-CAVALCANTE,KELMA M.S.; LIMA,REBECA L. DE; PEREIRA JÚNIOR,FRANCISCO N.; SOUSA,MÁRCIA B. DE; VIANA,FRANCISCO A.; NAGANO,CELSO S.; NASCIMENTO,KYRIA S. DO; CAVADA,BENILDO S.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA. |
Natural antioxidants found in marine macroalgae are bioactive compounds known to play an important role in the prevention of diseases associated with aging cells protecting them against the oxidative damage. The purpose of this study was to evaluate the antioxidant and cytotoxic activity of ethanolic extracts of two species of red seaweeds, Amansia multifida and Meristiella echinocarpa. In vitro antioxidant activity was determined by DPPH radical scavenging assay, ferric-reducing antioxidant power (FRAP) assay, ferrous ion chelating (FIC) assay, β-carotene bleaching (BCB) assay and total phenolic content (TPC) quantification. Cytotoxicity was evaluated with the brine shrimp Artemia sp. lethality test. The TPC values observed in the present study indicated... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Bioactive compounds; Cytotoxic; Phenolic compounds; Rhodophyta. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100251 |
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ALENCAR,DANIEL B.; MELO,ARTHUR A.; SILVA,GISELLE C.; LIMA,REBECA L.; PIRES-CAVALCANTE,KELMA M.S.; CARNEIRO,RÔMULO F.; RABELO,ADRIANA S.; SOUSA,OSCARINA V.; VIEIRA,REGINE H.S.F.; VIANA,FRANCISCO A.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA. |
Marine invertebrates are capable of synthesizing bioactive compounds, which may be beneficial to human health. The aim of this study was to evaluate the antioxidant, hemolytic, antimicrobial and cytotoxic activities of crude extract (70% EtOH), and dichloromethane (DCM), ethyl acetate (EtOAc), and aqueous (Aq) fractions of the marine zoanthid Palythoa caribaeorum. The phenolic compound contents of the crude extract, DCM, EtOAc and Aq fractions were 12.33, 18.17, 10.53, and 3.18 mg GAE per gram, respectively. DPPH radical scavenging activity showed slight variation. IC50 of crude extract, DCM, EtOAc and Aq fractions were 11.13, 11.25, 11.74, and 11.28 µg mL-1, respectively. Among the sample, ferrous ion chelating was the highest in crude extract (IC50... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biological activity; Marine invertebrate; Natural product; Sphenopidae. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000201113 |
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PEREIRA,RAFAEL; PEREIRA,ANNA L.; FERREIRA,MARCILIO M.; FONTENELLE,RAQUEL O.S.; SAKER-SAMPAIO,SILVANA; SANTOS,HÉLCIO S.; BANDEIRA,PAULO N.; VASCONCELOS,MAYRON A.; QUEIROZ,JOSÉ A.N.; BRAZ-FILHO,RAIMUNDO; TEIXEIRA,EDSON H.. |
Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Antioxidant activity; Essential oil; Isoflavone; Myroxylon peruiferum. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
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ALENCAR,DANIEL B. DE; DINIZ,JAÉCIO C.; ROCHA,SIMONE A.S.; PIRES-CAVALCANTE,KELMA M.S.; LIMA,REBECA L. DE; SOUSA,KAROLINA C. DE; FREITAS,JEFFERSON O.; BEZERRA,RAYSSA M.; BARACHO,BÁRBARA M.; SAMPAIO,ALEXANDRE H.; VIANA,FRANCISCO A.; SAKER-SAMPAIO,SILVANA. |
ABSTRACT This study evaluated the chemical composition and antioxidant activity of fatty acids from the marine red algae Pterocladiella capillacea (S. G. Gmelin) Santelices & Hommersand 1997 and Osmundaria obtusiloba (C. Agardh) R. E. Norris 1991. The gas chromatography mass spectrometry (GC-MS) identified nine fatty acids in the two species. The major fatty acids of P. capillacea and O. obtusiloba were palmitic acid, oleic acid, arachidonic acid and eicosapentaenoic acid. The DPPH radical scavenging capacity of fatty acids was moderate ranging from 25.90% to 29.97%. Fatty acids from P. capillacea (31.18%) had a moderate ferrous ions chelating activity (FIC), while in O. obtusiloba (17.17%), was weak. The ferric reducing antioxidant power (FRAP) of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fatty acids; Antioxidant activity; Palmitic acid; Rhodophyta. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100449 |
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