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| FERNANDES,JULYANE B.M.; CELESTINO,MAÍSA T.; TAVARES,MARIA I.B.; FREITAS,ZAIDA M.F.; SANTOS,ELISABETE P. DOS; RICCI JÚNIOR,EDUARDO; MONTEIRO,MARIANA S.S.B.. |
| Abstract: Tapioca starch (TS) is produced from Cassaca roots and it is differentiated from other starches because it contains about 17–20% amylase and low amount of residual substances. Propranolol (POP) is a non-selective beta-adrenergic blocking agent and it is in the World Health Organization’s List of Essential Medicines. The aim of this work was to investigate the potential of TS in the development of POP tablets by means of direct compression. Its evaluation was performed by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) relaxometry, scanning electron microscopy (SEM), uniformity of weight, drug content, disintegration, friability, hardness, dissolution test and drug release kinetics. The TS... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tapioca starch; Propranolol; Tablet; NMR relaxation. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100806 |
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