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Acute and chronic toxicity of the benzodiazepine diazepam to the tropical crustacean Mysidopsis juniae 42
SILVA,ALLYSON Q. DA; NILIN,JEAMYLLE; LOUREIRO,SUSANA; COSTA-LOTUFO,LETICIA V..
Abstract Pharmaceuticals occur in the environment due to their excessive consumption and the inefficiency of treatment plants to degrade, inactivate or remove them. Diazepam (DZP) stands out as the most consumed benzodiazepine, and induces sedative effects and reduces anxiety. Considering its potential appearance in several environmental compartments, the aim of the present study was to determine the effects of DZP under acute and chronic exposures on the mysid Mysidopsis juniae. Mortality was assessed using an acute toxicity test and a LC50 of 3.7 ± 0.5 mg·L-1was derived. The mass and length of the mysids was recorded in the chronic exposure to test for sublethal effects, and concentrations of 0.25 and 0.5 mg·L-1 of DZP affected mysids length and dry...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Emerging contaminants; Mysids; Sublethal effects; Pharmaceuticals.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100713
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