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Effects of static magnetic field exposure on hematological and biochemical parameters in rats BABT
Amara,Salem; Abdelmelek,Hafedh; Salem,Mohamed Ben; Abidi,Rached; Sakly,Mohsen.
The present work was undertaken in order to investigate the effects of static magnetic field (SMF) on growth rates, hematopoiesis, plasmatic proteins levels, glucose concentration, lactate dehydrogenase (LDH) and transaminases activities in male rats. Sub-acute exposure of rats during 5 consecutive days to SMF (1h/day at 128mT) induced an increase of plasma LDH activity (+38%, p<0.05), and glucose concentration (+31%, p<0.05), whereas haematological parameters, protein levels, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities remained unchanged. SMF exposure of rats during 30 consecutive days (1hour/day at 128mT) decreased significantly growth rates by the second week and increased significantly the plasmatic total...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Static Magnetic Field; Transaminases; Haematopoiesis; Glucose; Rat.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000700005
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Pituitary Adenylate Cyclase Activating Peptide (1-38) and its analog (Acetyl-[Ala15, Ala20] PACAP 38-polyamide) reverse methacholine airway hyperresponsiveness in rats BJPS
Tlili,Mounira; Rouatbi,Sonia; Gandia,Fedoua; Hallegue,Dorsaf; Sriha,Badreddine; Yacoubi,Mohamed Taher; Krichah,Raja; Sakly,Mohsen; Rhouma,Khémais Ben; Vaudry,David; Wurtz,Olivier; Tebourbi,Olfa.
The aim of this study was to investigate both functionally and structurally bronchodilator effects of Pituitary adenylate cyclase activating peptide (PACAP38) and acetyl-[Ala15, Ala20] PACAP38-polyamide, a potent PACAP38 analog, in rats challenged by methacholine (MeCh). Male Wistar rats were divided randomly into five groups. Groups 1 and 2 inhaled respectively aerosols of saline or increasing doses of MeCh (0.5, 1, 2.12, 4.25, 8.5, 17, 34 and 68mg/L). The other groups received terbutaline (Terb) (250 µg/rat) (10-6 M), PACAP38 (50 µg/rat) (0.1 mM) or PACAP38 analog (50 µg/rat) associated to MeCh from the dose of 4.25 mg/L. Total lung resistances (RL) were recorded before and 2 min after MeCh administration by pneumomultitest equipment. MeCh administration...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pituitary adenylate cyclase activating peptide/effects/inflammatory lung diseases; Pituitary adenylate cyclase/analogs/effects in inflammatory lung diseases; Methacholine; Bronchodilators/effects; Inflammatory lung diseases/treatment.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300681
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