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| Oliveira Neto,M.G.; Santos,H.A.; Fraga,R.E.; Pacheco,A.S.; Sampaio,G.P.; Moura-Costa,L.F.; Meyer,R.; Silva,M. Costa; Trindade,S.C.; Vale,V.L.C.. |
| ABSTRACT This study aimed to evaluate aspects of host immune response using an experimental infection model of Corynebacterium pseudotuberculosis (CP) in C57/Black6 wild-type and knockout for nitric oxide (KO-NO) mice. 28 mice were evaluated: 4 wild-type controls; 10 wild-type infected with CP; 4 KO-NO controls; 10 KO-NO infected with CP. Infection procedures were carried out by intraperitoneal inoculation using 107. Infected C57/Black6 KO-NO mice began to die after the 5° day post-inoculation, up until the 14º day. Neutrophils were found in increased numbers in the infiltrate of KO-NO murine peritoneal cavities. Examination of splenic tissue revealed an accumulation of lymphocytes, predominantly CD8 T-cells, in experimental animal groups. KO-NO animals... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nitric oxid; Knockout mice; Corynebacterium pseudotuberculosis; Caseous limphadenitis. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601565 |
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| Torres,A.J.L.; Angelo,A.L.D.; Netto,E.M.; Sampaio,G.P.; Souza,D.F.C.; Inocêncio,L.A.; Lemos,J.A.R.; Brites,C.. |
| This study defined the normal variation range for different subsets of T-lymphocyte cells count in two different Brazilian regions. We analysed the T-lymphocytes subpopulations (CD3+, CD4+, CD8+) in blood donors of two Brazilian cities, located in North (Belem, capital state of Para, indian background) and Northeast (Salvador, capital state od Bahia, African background) regions of Brazil. Results were compared according to gender, stress level (sleep time lower than 8 hours/day), smoking, and alcohol intake. Lymphocytes subpopulations were measured by flow cytometry. Five hundred twenty-six blood donors from two Brazilians cities participated in the study: 450 samples from Bahia and 76 samples from Pará. Most (60%) were men, 59% reported alcohol intake,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: CD4; CD8; Blood donors; Reference values; Brazil. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300013 |
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