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	Provedor de dados BJPS (1) Autor Sangeetha,Ragupathy (1) Palavra-chave Antidiabetic (1) Gracilaria corticata (1) Luteolin (1) Synergistic (1) Α-amylase (1) Α-glucosidase (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2020 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Independent and synergistic activity of the flavonoids of Gracilaria corticata as promising antidiabetic agents BJPS Sangeetha,Ragupathy. The therapeutic approaches for Type 2 Diabetes Mellitus rely most on the usage of oral hypoglycaemic drugs. These drugs have adverse side effects and hence alternative medicines are continuously explored. The present study intends to investigate the antidiabetic potential of the flavonoids present in Gracilaria corticata. The flavonoids were isolated (FEGC) and their inhibitory activity on the carbohydrate hydrolysing enzymes such as α-amylase and α-glucosidase was analysed. The flavonoids were found to inhibit α-amylase and α-glucosidase with an IC50 value of 302 µg and 75 µg respectively. The synergistic effect of FEGC and luteolin was also investigated and the results show that both FEGC and luteolin inhibited synergistically at half their IC50 values.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Α-amylase; Α-glucosidase; Antidiabetic; Gracilaria corticata; Luteolin; Synergistic. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100618 Registros recuperados: 1 Primeira ... 1 ... Última

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