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| Vilar,Juliana Brandstetter; D'Oliveira,Maria Inez Prudente; Santos,Suzana da Costa; Chen,Lee Chen. |
| Stryphnodendron adstringens (Mart.) Coville, 1910 is a small tree, distributed widely throughout the Cerrado region of Brazil and named "barbatimão" by the Tupi-Guarani tribes, which presents astringent properties. Its ethnopharmacological uses comprise, among others, anti-inflammatory and wound healing action, and it is used in the treatment of diarrhea and gynecological problems. The phytotherapeutic use of 'barbatimão' is largely related to its tannin content, which is abundant in its bark. The main goal of the present study was to evaluate the cytotoxic, mutagenic, and genotoxic potential of the lyophilized solution of the stem bark of S. adstringens, using the Ames test, the SOS-Inductest and the SOS-Chromotest. S. adstringens presented cytotoxic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Stryphnodendron adstringens/cytotoxicity; Stryphnodendron adstringens/genotoxicity; Barbatimão/phytochemical study. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400010 |
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| Moura,Léa Resende; Martins,Aparecida Conceição; Vaz,Liliam Aparecida da Rocha; Orpinelli,Stiwens Roberto Trevisan; Silva,Thiago Lopes da; Faleiro,Mariana Batista Rodrigues; Santos,Suzana da Costa; Moura,Veridiana Maria Briagnezi Dignani de. |
| O objetivo deste estudo foi avaliar o efeito antioxidante do extrato hidroalcoolico da casca do pequi (EHCP) em ratos após a administração de doxorrubicina (DOX). Foram utilizados ratos da raça Wistar, distribuídos em quatro grupos, sendo que os animais do G1 (n=6) receberam água e solução salina (grupo controle), G2 (n=7) EHCP e solução salina, G3 (n=7) água e DOX e G4 (n=6) EHCP e DOX. O EHCP foi administrado por gavagem durante 10 dias aos ratos dos grupos G2 e G4 e água aos dos G1 e G3. DOX na dose de 10mg kg-1 e solução salina 0,9% foram administradas por via intravenosa no dia sete após o início do experimento aos animais de G3 e G4 e aos de G1 e G2, respectivamente. Foram avaliados peso e taxa de mortalidade. Dez dias após o início do experimento,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estresse oxidativo; Cardiotoxicidade; Antracilcinas; Antioxidante; Fruto do cerrado. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000100017 |
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| Pereira,Luciane Dias; Ascheri,Diego Palmiro Ramirez; Bastos,Suely Miranda Cavalcante; Ascheri,José Luis Ramírez; Santos,Suzana da Costa. |
| ABSTRACT Jaboticaba is a fruit with high nutritional potential with beneficial effects for health. The aims of this work were the optimization of the extraction of phenolic compounds (PhC) from freeze-dried jaboticaba peel (FJP) as a function of the stirring time (ST) and solvent volume (SV) and to study the edaphic effect on the physical-chemical composition of FJP from five orchards. In the first stage, a 2-factor, 2-level central composite designs combined with the Response Surface Methodology and desirability function was used. In the second stage, a one-way analysis of variance was used to investigate the edaphic effect on the responses. Total phenols (Tph), tannins (Ta), total monomeric anthocyanins (TMA), color index (CI) and tone responses (Ton)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Myrciaria cauliflora; Ultrasound; Response surface methodology; Physical-chemical properties.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542018000400431 |
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