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| Nejad,Khojasteh Hoseiny; Sarkaki,Alireza; Dianat,Mahin; Farbood,Yaghoob; Badavi,Mohammad; Gharib-Naseri,Mohammad Kazem. |
| ABSTRACT Cerebral ischemia commonly occurs when the blood flow to the entire brain or some part of the brain is disrupted. Global cerebral ischemia attenuates the nucleus tractus solitaries (NTS) EEG rhythm, increases the free radicals production and brain inflammation. Ellagic acid (EA) has antioxidative and anti-inflammatory effects against neural damages. The aim of this study was to evaluate the role of ellagic acid on EEG power in the global cerebral ischemia.Rats were divided into four groups: SO (sham) received normal saline, EA+SO, I/R (normal saline + ischemia/reperfusion), and EA + I/R. EA (100 mg/kg, dissolved in normal saline) or normal saline was administered orally (gavage) for 10 days. Animal underwent to 20 minutes of ischemia followed by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ellagic acid; EEG; Antioxidant; Cerebral ischemia/reperfusion; Rat. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100446 |
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