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Longitudinal brain volumetric changes during one year in non-elderly healthy adults: a voxel-based morphometry study BJMBR
Guimarães,R.M.; Schaufelberger,M.S.; Santos,L.C.; Duran,F.L.S.; Menezes,P.R.; Scazufca,M.; Gouvea,M.T.V; Busatto,G.F..
Previous cross-sectional magnetic resonance imaging (MRI) studies of healthy aging in young adults have indicated the presence of significant inverse correlations between age and gray matter volumes, although not homogeneously across all brain regions. However, such cross-sectional studies have important limitations and there is a scarcity of detailed longitudinal MRI studies with repeated measures obtained in the same individuals in order to investigate regional gray matter changes during short periods of time in non-elderly healthy adults. In the present study, 52 healthy young adults aged 18 to 50 years (27 males and 25 females) were followed with repeated MRI acquisitions over approximately 15 months. Gray matter volumes were compared between the two...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gray matter; Aging; Voxel-based morphometry; Magnetic resonance imaging; Prefrontal cortex; Hippocampus.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600007
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