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Firocoxib on aqueous humor prostaglandin E 2 levels for controlling experimentally-induced breakdown of blood-aqueous barrier in healthy and Toxoplasma gondii -seropositive cats Ciência Rural
Schroder,Deise Cristine; Stocco,Matias Bassinello; Isoton,Deborah de Arruda; Silva,Carla Patricia Amarante e; Braga,Ísis Assis; Silva,Érica Pereira da; Maciel,Camila do Espírito Santo; Maruyama,Fernanda Harumi; Nakazato,Luciano; Aguiar,Daniel Moura de; Mendonça,Adriane Jorge; Ribeiro,Alexandre Pinto.
ABSTRACT: This study aimed to evaluate the effects of firocoxib for controlling experimentally-induced breakdown of the blood-aqueous barrier in healthy and Toxoplasma gondii -seropositive cats. Thirty two cats with no ocular abnormalities were used. Groups (n=8/each) were formed with healthy cats that received 5mg g-1 of oral firocoxib (FH) or no treatment (CH) on day 0; seropositive cats for anti -T. gondii specific immunoglobulin G (IgG) were grouped (n=8/each) and treated in a similar fashion (FT and CT). On day 1, cats of all groups received the same treatment protocol, and 1h later, aqueocentesis was performed under general anesthesia (M0). Following 1h, the same procedure was repeated (M1). Quantitation of aqueous humor total protein and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aqueous humor; Intraocular inflammation; NSADs; Toxoplasmosis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601053
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Effects of tramadol and acepromazine on intraocular pressure and pupil diameter in young healthy cats Ciência Rural
Schroder,Deise Cristine; Monteiro,Bianca Garay; Pytlak,Deborah Braga; Souza,Mayara Carvalho de; Mendonça,Adriane Jorge; Ribeiro,Alexandre Pinto.
ABSTRACT: This study aimed to investigate the effects of the systemic administration of acepromazine, tramadol and the association of both on intraocular pressure (IOP) and pupil diameter (PD) in young healthy cats. Cats were randomly allocated into three groups (n=10/each) and intramuscular acepromazine (AG), tramadol (TG) or acepromazine combined with tramadol (ATG) were injected. PD (electronic caliper) and IOP (applanation tonometry) were assessed before (baseline) and following 15, 30, 60, and 120 minutes of treatments. It was verified that in AG, PD decreased significantly from time point 30 to 120 (P=0.002), but such reduction did not differ significantly from baseline (P=0.89). In TG, PD increased significantly from the first 15 minutes, until the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Opioid; Phenothiazinic; Mydriasis; Intraocular surgeries; Cats.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000300601
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