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Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety 56
Brenes,J.C.; Broiz,A.C.; Bassi,G.S.; Schwarting,R.K.W.; Brandão,M.L..
Electrical stimulation of midbrain tectum structures, particularly the dorsal periaqueductal gray (dPAG) and inferior colliculus (IC), produces defensive responses, such as freezing and escape behavior. Freezing also ensues after termination of dPAG stimulation (post-stimulation freezing). These defensive reaction responses are critically mediated by γ-aminobutyric acid and 5-hydroxytryptamine mechanisms in the midbrain tectum. Neurokinins (NKs) also play a role in the mediation of dPAG stimulation-evoked fear, but how NK receptors are involved in the global processing and expression of fear at the level of the midbrain tectum is yet unclear. The present study investigated the role of NK-1 receptors in unconditioned defensive behavior induced by electrical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neurokinin-1 receptors; Dorsal periaqueductal gray; Spantide; Unconditioned fear; Elevated plus maze; Ultrasonic vocalizations.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400009
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On the relationships between ultrasonic calling and anxiety-related behavior in rats 56
Schwarting,R.K.W.; Wöhr,M..
In the present review, the phenomenon of ultrasonic vocalization in rats will be outlined, including the three classes of vocalizations, namely 40-kHz calls of pups, and 22- and 50-kHz calls of juvenile and adult rats, their general relevance to behavioral neuroscience, and their special relevance to research on anxiety, fear, and defense mechanisms. Here, the emphasis will be placed on 40- and 22-kHz calls, since they are typical for various situations with aversive properties. Among other topics, we will discuss whether such behavioral signals can index a certain affective state, and how these signals can be used in social neuroscience, especially with respect to communication. Furthermore, we will address the phenomenon of inter-individual variability...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ultrasonic vocalization; Anxiety; Fear; Communication; Social behavior.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400008
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