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| Tomasini-Grotto,Rejane-Maria; Montes,Brigitte; Triglia,Denise; Torres- Braconi,Carla; Aliano-Block,Juliana; Zanotto,Paolo M. de A.; Pardini,Maria- Inèsde M. C.; Segondy,Michel. |
| The diversity of the V3 loop tip motif sequences of HIV-1 subtype B was analyzed in patients from Botucatu (Brazil) and Montpellier (France). Overall, 37 tetrameric tip motifs were identified, 28 and 17 of them being recognized in Brazilian and French patients, respectively. The GPGR (P) motif was predominant in French but not in Brazilian patients (53.5% vs 31.0%), whereas the GWGR (W) motif was frequent in Brazilian patients (23.0%) and absent in French patients. Three tip motif groups were considered: P, W, and non-P non-W groups. The distribution of HIV-1 isolates into the three groups was significantly different between isolates from Botucatu and from Montpellier (P < 0.001). A higher proportion of CXCR4-using HIV-1 (X4 variants) was observed in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV-1; V3 loop; Genetic diversity; Brazil; France. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300024 |
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