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Weissmann,Leonardo; Picone,Camila de Melo; Gouvêa,Michele Soares Gomes; Ferreira,Paulo Roberto Abrão; Viana,Mônica Salum Valverde Borsoi; Pinho,João Renato Rebello; Cassenote,Alex Jones Flores; Segurado,Aluísio Cotrim. |
ABSTRACT Background: Antiretroviral therapy (ART) has decreased AIDS incidence and mortality, rendering comorbidities, such as hepatitis B more relevant for people living with human immunodeficiency virus (HIV). Since antiretroviral drugs may also inhibit hepatitis B virus (HBV) replication, analyzing the impact of ART on management of hepatitis B in this population is important. Objective: To assess HBV viremia among HIV/HBV coinfected individuals on ART and its associated factors. Method: For this cross-sectional study, HIV/HBV-coinfected individuals, aged over 18 years, who were on ART for over six months and receiving care at an outpatient clinic in São Paulo were recruited. Sociodemographic characteristics, information about viral exposure,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV infections Hepatitis B Coinfection Antiretroviral agents Viremia DNA; Viral. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000600441 |
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Vidal,José Ernesto; Song,Alice Tung Wan; Matos,Maria Laura; Bartmann,Daniel; Anjos,Guilherme dos; Miranda,Érique José Peixoto de; Freitas,Ângela Carvalho; Dalben,Mirian de Freitas; Santana,Claudinei; Segurado,Aluísio Cotrim; Barreto,Cláudia Cortese; Hernández,Adrián Vladimir. |
Tipo: Info:eu-repo/semantics/other |
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Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300017 |
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Vidal,José Ernesto; Song,Alice Tung Wan; Matos,Maria Laura; Bartmann,Daniel; Anjos,Guilherme dos; Miranda,Érique José Peixoto de; Freitas,Ângela Carvalho; Dalben,Mirian de Freitas; Santana,Claudinei; Segurado,Aluísio Cotrim; Barreto,Cláudia Cortese; Hernández,Adrián Vladimir. |
OBJECTIVES: To assess the virologic and immunological response of darunavir/ritonavir plus optimized background therapy in highly antiretroviral-experienced HIV-infected patients in Brazil. METHODS: Prospective cohort study carried out in a tertiary center in Sao Paulo, Brazil. Three-class antiretroviral-experienced patients with confirmed virologic failure began darunavir/ritonavir plus optimized background therapy (nucleoside/tide reverse transcriptase inhibitors ± raltegravir ± enfuvirtide ± maraviroc) after performing a genotypic resistance assay. Clinical evaluation and laboratory tests were collected at baseline and at weeks 12, 24, and 48. Multivariate analysis was performed to identify predictors of virologic response at 48 weeks. RESULTS:... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Highly active antiretroviral therapy; Darunavir; Acquired immunodeficiency syndrome; Developing countries. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000100007 |
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