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	Provedor de dados JBAG (6) Autor Seoane,A (6) Ferreira,V (2) Picco,SJ (2) Anchordoquy,JM (1) Anchordoquy,JP (1) Boffi,FM (1) Crudeli,C (1) Fazzio,LE (1) Furnus,CC (1) López,RA (1) Mattioli,GA (1) Muriel,M (1) Muriel,MG (1) Padula,G (1) Palacios,A (1) Peral García,P (1) Peral-García,P (1) Picco,S.J (1) Ponzinibbio,M.V (1) Ponzinibbio,MV (1) Mais... Palavra-chave Comet assay (2) Ionizing radiation (2) Apoptosis (1) Bacterial infections (1) Children (1) Cumulus cells (1) DNA damage (1) Daño en el ADN (1) Ejercicio (1) Equinos Sangre Pura de Carrera (1) In vitro (1) Low dose (1) Low radiation dose (1) Protein energy malnutrition (1) Structural chromosome aberrations (1) Zinc (1) Mais... Tipo do documento Info:eu-repo/semantics/article (6) Ano 2016 (1) 2011 (1) 2008 (3) 2007 (1) País Argentina (6) Idioma Inglês (5) Espanhol (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 6 Primeira ... 1 ... Última Chromosomal effects of infections in malnourished and eutrophic children of Gran La Plata JBAG Padula,G; Seoane,A. The aim of this study was to assess the induction of structural chromosomal aberrations in peripheral blood lymphocytes of malnourished and eutrophic children with bacterial infections. Thirty-six infants concurrent to the Hospital Interzonal de Agudos y Crónicos Dr. Alejandro Korn, La Plata, Argentina were included in this analysis; 11 infected and malnourished (IM), 7 infected and eutrophic (IE) and 18 non-infected and eutrophic (NE). Children aged 1-60 months. Anthropometric and clinic evaluation were performed to assess nutritional condition. We scored structural chromosome aberrations (SCA) in 100 metaphases per individual. Statistical analysis was performed by the Epi Dat 3.0 (OPS-OMS, 2003), through «Test de Diferencias entre dos proporciones... Tipo: Info:eu-repo/semantics/article Palavras-chave: Protein energy malnutrition; Bacterial infections; Structural chromosome aberrations; Children. Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332008000100003 DNA damage induced by exercise in middle gluteal muscle of thoroughbreds horses JBAG Boffi,FM; Muriel,MG; López,RA; Ferreira,V; Seoane,A; Picco,SJ. It is well known that two classical consequences of severe exercise are soreness and stiffness. Both consequences develop in the days following severe exercise. The objective of the present work was to establish the association between DNA damage, the energetic metabolism and the effects of the generation of oxygen free radicals in middle gluteal muscle of horses, measured after a severe exercise bout on a treadmill. Four thoroughbreds, ranging in aged from 3 to 4 years old were used for this study. The test consisted in warming-up, severe exercise, and cooling down. Venous blood samples were withdrawn via a catheter from the jugular vein before and at 5 min, 30 min, 45 min and 24 h post-exercise. Muscle biopsy samples were obtained from the middle gluteal... Tipo: Info:eu-repo/semantics/article Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332007000200001 Dinámica del daño en el ADN en leucocitos de equinos sangre pura de carrera sometidos a un test de ejercicio estandarizado JBAG Muriel,M; Seoane,A; Savignone,C; Palacios,A; Ferreira,V; Picco,S.J. Esta claramente establecido que durante el ejercicio se produce un aumento en la produccion de radicales libres que pueden romper el equilibrio oxido-reductor y causar dano en el ADN. El objetivo del presente trabajo fue establecer la existencia de dano en el ADN en leucocitos circulantes de equinos sometidos a ejercicio sub-maximo mediante el empleo del ensayo cometa. Se usaron cinco equinos sometidos a un test estandarizado de ejercicio, a los que se les extrajeron muestras antes de comenzar el ejercicio, a los 8,5 m/s, a los 15 m/s, y 1 y 30 min post-ejercicio. Simultaneamente se realizo una ergoespirometria continua para determinar el consumo de oxigeno durante el test de ejercicio. La frecuencia de celulas con dano en el ADN fue 0,448, 0,537, 0,617,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Equinos Sangre Pura de Carrera; Ejercicio; Daño en el ADN. Ano: 2016 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332016000100003 Cytogenetic and cytomolecular delayed damage induced in human fibroblasts by low X-ray doses JBAG Ponzinibbio,MV; Crudeli,C; Peral García,P; Seoane,A. During the last decade several reports have provided evidence on the non-targeted effects of ionizing radiation. In this study, we have analyzed the delayed DNA damage induced by ionizing radiation in MRC-5 Human fibroblasts cultured in vitro. MRC-5 cells were irradiated with 10 and 50 milligrays (mGy) and analyzed immediately after exposure, and at passages 6 and 12 post-radiation by means of comet assay, micronucleus analysis and γ-H2AX foci formation. Cytogenetic and cytomolecular damage was analysed at every sample point comparing irradiated and control cells. No significant damage differences were found among samples from all passages of treatments. Our results suggest that even at low doses, ionizing radiation could induce delayed damage.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ionizing radiation; Low radiation dose; DNA damage. Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332008000100006 Effect of zinc on DNA integrity of cumulus cells during oocyte in Vitro maturation JBAG Picco,SJ; Seoane,A; Anchordoquy,JM; Anchordoquy,JP; Rosa,D; Fazzio,LE; Mattioli,GA; Furnus,CC. Zinc is an essential trace element. It has been known that a non adequate level of zinc can alter not only gene expression but also a variety of cellular functions with severe consequences on animal health. Little is known about the role of zinc on the reproductive performance of bovines, especially in oocyte maturation. The objective of the present study was to evaluate the impact of different zinc concentrations added to culture medium, on the DNA integrity of bovine cumulus cells during in vitro maturation of oocytes. Cumulus-oocyte coplexes obtained from an abattoir were cultured in IVM mediums containing 30 (G1), 70 (G2), 110 (G3) and 150 (G4) μg/dl. At the end of IVM, cumulus cells were processed for Comet Assay. Result obtained with the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Zinc; Cumulus cells; Comet assay. Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332008000200004 In vitro apprach to the study of chronic exposure to low does of X-rays JBAG Ponzinibbio,M.V; Peral-García,P; Seoane,A. The present research was undertaken in order to study the effect of repeated low doses of radiation on two different cell lines from the same species. An in vitro model test was developed to avoid the influence of the confounding factors affecting epidemiological studies and to simulate a chronic exposure (50 mSv of x-rays during ten consecutive days). Comet assay and early apoptosis were analyzed immediately after exposure and after chronic irradiation. Sequential irradiation induced an increase of cells showing DNA damage. Index Damage was higher than that of the controls in both cell lines immediately after exposure and after chronic irradiation. These differences between exposed and control cells were statistically significant only for the transformed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Apoptosis; Comet assay; In vitro; Ionizing radiation; Low dose. Ano: 2011 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332011000200004 Registros recuperados: 6 Primeira ... 1 ... Última

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