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Immune reconstitution syndrome in patients treated for HIV and tuberculosis in Rio de Janeiro 55
Serra,Fabiana C.; Hadad,David; Orofino,Renata L.; Marinho,Flavia; Lourenço,Cristina; Morgado,Mariza; Rolla,Valeria.
We made a retrospective longitudinal study from January 2000 to January 2003 to examine cases of immune reconstitution syndrome (IRS) and its incidence rate in tuberculosis (TB)-human immunodeficiency virus (HIV) co-infected patients. The incidence rate (IR) was calculated using a Poisson regression. The confidence interval (CI) that was stipulated was 95%. IRS occurred in 10/84 HIV and TB-positive patients; nine of them were on highly active anti-retroviral therapy (HAART) during a mean of 61.7 (±59) days following the introduction of antiretrovirals. Lymph-node enlargement was the sole clinical manifestation. CD4 counts were <100 cells/mm³in 50% of the patients, at the time of TB diagnosis. All but two patients were treated with prednisone, and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; Immune reconstitution syndrome; Tuberculosis; HAART; Lymph node enlargement; Paradoxical reaction.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500004
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