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Congenital toxoplasmosis transmitted by human immunodeficiency-virus infected women BJID
Azevedo,Kátia Martins Lopes de; Setúbal,Sérgio; Lopes,Vania Gloria Silami; Camacho,Luiz Antônio Bastos; Oliveira,Solange Artimos de.
We report the occurrence of congenital toxoplasmosis in three infants born to HIV infected women who had high anti-toxoplasma IgG and negative IgM during pregnancy. We briefly reviewed available literature and discussed the possible transmission mechanisms of congenital toxoplasmosis among HIV infected pregnant women. Serum samples were tested for Toxoplasma gondii IgM and IgG antibodies using commercial enzyme immunoassay and IgG-avidity tests. In the first case, fetal death occurred at 28th week of gestation. In the second case, congenital toxoplasmosis was diagnosis at 6th month of life; and in the third case, an HIV-infected newborn, congenital toxoplasmosis was asymptomatic. These cases point out to the possibility of enhanced maternal-fetal...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Congenital toxoplasmosis; Human immunodeficiency-virus; Prevention; AIDS.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200014
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Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil BJID
Fernandes,Márcia Antunes; Batista,Giovanni Inácio; Carlos,Juliano da Costa Silveira; Gomes,Ivete Martins; Azevedo,Kátia Martins Lopes de; Setúbal,Sérgio; Oliveira,Solange Artimos de; Velarde,Luis Guilhermo Coca; Cardoso,Claudete Aparecida Araújo.
OBJECTIVE: Compare the anti-T. gondii IgG titer between HIV-1 infected and non HIV-1 infected pregnant women and report three cases of congenital toxoplasmosis resulting from reactivation of infection during pregnancy of HIV-1 infected women. METHODS: This study was conducted among 2,270 pregnant women with chronic Toxoplasma gondii infection (absence of IgM and presence of IgG), including 82 HIV-1 infected and 2,188 non-infected women. RESULTS: The average anti-T. gondii IgG titer was 127 for the 2,188 non-HIV-1 infected women, and 227 for the 82 HIV-1-infected women (p = 0,007). These results suggested that higher anti-T. gondii IgG titers in HIV-1-infected pregnant women may not be indicative of an elevated risk for fetal infection. In this study three...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Toxoplasma Toxoplasmosis; Congenital HIV infections.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200011
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