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| Maimaitimin,Kuerbanjiang; Jiang,Zhihui; Aierken,Aili; Shayibuzhati,Mikeremu; Zhang,Xiaoying. |
| Overconsumption of alcohol leads to alcoholic liver disease (ALD). Natural compounds have been investigated previously for their hepatoprotective activities against liver injury. This study investigated the protective effect of Alhagi sparsifolia on ALD. Alcohol was administered to mice for three consecutive days; either alone or in combination with Alhagi sparsifolia extract (150, 300, 600 mg/kg). Serum aspartate aminotransferase and alanine transaminase as biomarkers of liver injury, the content of malonaldehyde, hydrogen peroxide (H2O2) and glutathione which indicated the redox status of liver and the antioxidant enzyme activity of super oxide dismutase were detected, respectively. Moreover, the expression of protein cytochrome P450 2E1 (CYP2E1) the key... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alcoholic liver disease; Alhagi sparsifolia; Hepatoprotective effect; Antioxidantion; CYP2E1. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300625 |
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