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| Idrees,Muhammad; Siddiqi,Abdul Rauf; Ajmal,Muhammad; Akram,Muhammad; Khalid,Rana Rehan; Hussain,Alamdar; Qamar,Raheel; Bokhari,Habib. |
| Abstract Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis of a variety of diseases including atherosclerosis. Conversely, mutations in the low density lipoprotein receptor (LDLR) result in failure of receptor mediated endocytosis of LDL leading to its elevated plasma levels and onset of familial hypercholesterolemia (FH). In the current study we investigated the role of PON1 polymorphisms rs662; c.575A > G (p.Gln192Arg) and rs854560; c.163T > A (p.Leu55Met) in a large family having FH patients harboring a functional mutation in LDLR. Genotypes were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Paraoxonase-1; Hypercholesteremia; Arylesterase; LDLR mutation. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000400570 |
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| Siddiqi,Abdul Rauf; Rafi,Athar; Naz,Falak; Masih,Rafique; Ahmad,Iftikhar; Jilani,Ghulam. |
| The peach fruit fly, Bactrocera zonata, is a significant pest of fruit and vegetable crops in South East Asia and Pacific region. Ccontrol strategies of fruit flies, relying chiefly on insecticides, have serious environmental consequences, disturbing the agro-ecosystem as well as eliminating natural enemies. This study was oriented at exploring the potential of turmeric, Curcuma longa, extracts to control the peach fruit fly. Freshly emerged female adults of Bactrocera zonata were continuously fed for 16 days on diet containing 1000, 500 and 250 ppm of acetone extract of Curcuma longa separately in laboratory cages. The extract caused 85.00, 66.67 and 56.67 percent mortality at 1000, 500 and 250 ppm respectively. The surviving females were mated and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Turmeric; Peach fruit fly; Bactrocera zonata; Solvent extracts; Mortality. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542011000600010 |
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