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Profile of IL-2, IL-4, IL-10, IFN- γ , TNF- α and KC-like cytokines in pregnant bitches 45
Feliciano,M.A.R.; Silva,A.S.L.; Crivelaro,R.M.; Oliveira,M.E.F.; Coutinho,L.N.; Vicente,W.R.R..
The aim of this study was to determine the profile of IL-2, IL-4, IL-10, IFN-γ, and TNF-α cytokines and KC-like cells (natural killer) in pregnant bitches, unpublished values for the species. A total of 27 females of the Shi Tzu, Pug, English Bulldog and French breeds, weighing 4-20kg and aged 4-6 years were used. Blood samples were collected from bitches during the anestrous and on the 2nd, 5th, 6th, 7th and 8th week of pregnancy. Serum levels of cytokines were measured by panel MILLIPLEX MAP (CCYTO-90K, MILLIPORE, Billerica, Massachusetts, USA) validated for dogs. Twenty four females showed physiological pregnancy and three bitches showed pathological pregnancy. There was no difference between cytokine values during anestrous and gestational weeks of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Immunity; Pregnancy.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000401067
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