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| Barros,Pedro Paulo; Silva,Gustavo Henrique da; Gonçalves,Gisele Mara Silva; Oliveira,Jessica Cristiane; Pagnan,Livia Gonçalves; Arco-e-Flexa,Luiza. |
| ABSTRACT Quercetin has potent antioxidant action and a hepatoprotective role. The aim of this study was to evaluate the hepatoprotective action of quercetin pretreatment in paracetamol-induced liver damage (PILD) and structural injury resulting from partial hepatectomy (PH). In the first model, Wistar rats received oral quercetin (50mg/kg/day) during 8 days. On the 8th day, 3g/kg paracetamol were added. In the second model, the same quercetin dose was given during 7 days and rats were submitted to PH on the 8th day. Blood samples were obtained for determination of enzyme levels. Liver, heart, kidney and lung tissue were also collected for assessment of quercetin biodistribution and/or histological analyses. The results obtained after PILD were more... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Quercetin; Paracetamol; Partial hepatectomy; ALT; AST. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100302 |
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| Gonçalves,Gisele Mara Silva; Silva,Gustavo Henrique da; Barros,Pedro Paulo; Srebernich,Silvana Mariana; Shiraishi,Cecilia Toyoko Cavalcanti; Camargos,Victória Rodrigues de; Lasca,Thais Barbiero. |
| Curcuma longais a ginger family aromatic herb (Zingiberaceae) whose rhizomes contain curcuminoid pigments, including curcumin, a compound known for its anti-inflammatory effects. The objective of this study was to obtain curcuminoid-rich extracts, develop topical formulations thereof, and assess the stability and skin permeation of these formulations. Curcuma longa extracts were obtained and used to develop formulations. Skin permeation studies were conducted in a modified Franz diffusion cell system, and skin retention of curcuminoid pigments was quantified in pig ear membrane. Prepared urea-containing gel-cream formulations were unstable, whereas all others had satisfactory stability and pseudoplastic rheological behavior. The amount of curcuminoid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Curcuma longa/pharmacognosy; Curcumin/use/topical anti-inflammatory; Cosmetics/use of natural products; Curcuminoid pigments; Skin penetration; Natural products/use in cosmetics. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400885 |
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| Silva,Gustavo Henrique da; Cunha,Fernando França da; Morais,Caio Vieira de; Freitas,Agnaldo Roberto de Jesus; Silva,Derly José Henriques da; Souza,Caetano Marciano de. |
| ABSTRACT Polyethylene mulch can cause serious problems in the environment. A promising alternative to polyethylene mulch is biodegradable mulch. Therefore, a two-year experiment was carried out with zucchini (Cucurbita pepo L.) during the cropping seasons of 2017 and 2018 in Southeast Brazil to investigate the effects of four soil mulching treatments (white polyethylene mulch: WP, black polyethylene mulch: BP, biodegradable mulch of brown recycled paper: RP and nonmulched: NM) and two wetted soil percentages (50 and 70% of the soil surface) using a randomized block design with five repetitions. The average water consumption of the zucchini was 157 mm in the WP treatment, 155 mm in the BP treatment, 155 mm in the WP treatment and 215 mm in the NM treatment.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biodegradability; Cucurbita pepo; Drip irrigation; Water saving.. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542020000100217 |
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