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| Cortez,Lucia Elaine Ranieri; Ferreira,Izabel Cristina Piloto; Lonardoni,Valdrinez Campana; Ferreira,Antonio Gilberto; Vieira,Paulo Cesar; Silva,Maria Fátima das Graças Fernandes da; Fernandes,João Batista; Cortez,Diógenes Aparicio Garcia. |
| The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Almeidea coerulea; Rutaceae; Indolopyridoquinazoline alkaloid; Anti-leishmanial activity. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008 |
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| Severino,Vanessa Gisele Pasqualotto; Silva,Maria Fátima das Graças Fernandes da; Lucarini,Rodrigo; Montanari,Lilian Bueno; Cunha,Wilson Roberto; Vinholis,Adriana Helena Chicharo; Martins,Carlos Henrique Gomes. |
| Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hortia oreadica; Rutaceae; Antibacterial activity; MIC; Oral pathogens. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000300015 |
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