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Evaluation of antinociceptive and anti-inflammatory activities of the topical preparation of Cipura paludosa (Iridaceae) Acta Amazonica
Silva Neto,José Antônio Paixão da; Menezes,Larissa Dias; Gomes,Gúbio Oliveira; Cunha,Elise Marques Freire; Azevedo,Mariângela Soares de; Ferreira,Vania Moraes; Silva,Mônica Valero da.
Alho do mato (Cipura paludosa, Iridaceae) is a medicinal plant found in the Amazon rain forest, North of Brazil. It has been used to treat algic, inflammatory and infectious processes. The aim of this study was to evaluate the anti-inflammatory and antinociceptive action of the crude Cipura paludosa ethanolic extract at concentrations ranging between 2.0 and 4.0% in Oil and Water cream formulations for topical use. The physical-chemical stability of the formulations was monitored over a six-month period with the use of accelerated stability tests. In order to evaluate the anti-inflammatory and antinociceptive activities, we used a paw edema test induced by carrageenan and a formalin test, respectively. The paw edema test showed that there was a statistical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oil and Water Cream; Medicinal plant; Paw edema test; Formalin test.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672014000200012
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