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	Provedor de dados BJMBR (3) Autor Silveira,T.R. (3) Almeida,H. (1) Bulhões,A.C. (1) Cerski,C.T.S. (1) Cerski,T. (1) Goldani,H.A.S. (1) Matte,U.S. (1) Mazzuca,R.B. (1) Motta,A. (1) Oliveira,F.S. (1) Santos,J.L. (1) Schwartsmann,G. (1) Zim,M.C.A. (1) Mais... Palavra-chave Biliary atresia (1) Carbon tetrachloride (1) Cirrhosis (1) Fibrogenesis (1) Hepatic necrosis (1) Hydrogen breath test (1) LCT polymorphism (1) Lactase-phlorizin hydrolase (1) Lactose intolerance (1) Liver biopsy (1) Milk intolerance (1) Neonatal cholestasis (1) Pentosan polysulfate (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2007 (1) 2002 (1) 1998 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia BJMBR Bulhões,A.C.; Goldani,H.A.S.; Oliveira,F.S.; Matte,U.S.; Mazzuca,R.B.; Silveira,T.R.. The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910. The objective of the present study was to assess the presence of these two mutations in Brazilian individuals with and without lactose malabsorption diagnosed by the hydrogen breath test (HBT). Ten milk-tolerant and 10 milk-intolerant individuals underwent the HBT after oral ingestion of 50 g lactose (equivalent to 1 L of milk). Analyses for C/T-13910 and G/A-22018 mutations were performed using a PCR-based method. Primers were designed for this study based on the GenBank sequence. The CT/GA, CT/AA, and TT/AA genotypes (lactase persistence) were found in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hydrogen breath test; Lactase-phlorizin hydrolase; Lactose intolerance; Milk intolerance; LCT polymorphism. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100004 Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats BJMBR Zim,M.C.A.; Silveira,T.R.; Schwartsmann,G.; Cerski,T.; Motta,A.. Few data are available in the literature regarding the effect of pentosan polysulfate (PPS) on normal and fibrotic rat livers. In addition, the combination of PPS and carbon tetrachloride (CCl4) has not been studied so far. The objective of this study was to assess the effect of PPS on rat livers treated or not with CCl4 for the induction of liver fibrosis. The study consisted of four stages: 1) hepatic fibrosis induction with CCl4 (N = 36 rats); 2) evaluation of the effect of PPS on CCl4-induced hepatic fibrosis (N = 36 rats); 3) evaluation of the effect of higher doses of PPS in combination with CCl4 (N = 50 rats); 4) evaluation of the presence of an enzymatic inductor effect by PPS (N = 18 rats) using the sodium pentobarbital test which indirectly... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cirrhosis; Fibrogenesis; Hepatic necrosis; Pentosan polysulfate; Carbon tetrachloride. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001100012 Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis BJMBR Santos,J.L.; Almeida,H.; Cerski,C.T.S.; Silveira,T.R.. The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which could discriminate between intra- and extrahepatic cholestasis. Forty-six liver biopsies (35 wedge biopsies and 11 percutaneous biopsies) and one specimen from a postmortem examination, all from patients hospitalized for neonatal cholestasis in the Pediatrics Service of Hospital de Clínicas de Porto Alegre, were prospectively studied using a specially designed histopathological protocol. At least 4 of 5 different stains were used, and 46 hepatic histopathological variables related to the differential... Tipo: Info:eu-repo/semantics/article Palavras-chave: Liver biopsy; Neonatal cholestasis; Biliary atresia. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000700005 Registros recuperados: 3 Primeira ... 1 ... Última

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