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| Tanaka,D.M.; Romano,M.M.D.; Carvalho,E.E.V.; Oliveira,L.F.L.; Souza,H.C.D.; Maciel,B.C.; Salgado,H.C.; Fazan-Júnior,R.; Simões,M.V.. |
| Determination of left ventricular ejection fraction (LVEF) using in vivo imaging is the cardiac functional parameter most frequently employed in preclinical research. However, there is considerable conflict regarding the effects of anesthetic agents on LVEF. This study aimed at assessing the effects of various anesthetic agents on LVEF in hamsters using transthoracic echocardiography. Twelve female hamsters were submitted to echocardiography imaging separated by 1-week intervals under the following conditions: 1) conscious animals, 2) animals anesthetized with isoflurane (inhaled ISO, 3 L/min), 3) animals anesthetized with thiopental (TP, 50 mg/kg, intraperitoneal), and 4) animals anesthetized with 100 mg/kg ketamine plus 10 mg/kg xylazine injected... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Echocardiography; Anesthetics; Systolic function; Hamsters. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001000602 |
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| Mejia,J.; Galvis-Alonso,O.Y.; Braga,J.; Corrêa,R.; Leite,J.P.; Simões,M.V.. |
| Single-photon emission computed tomography (SPECT) is a non-invasive imaging technique, which provides information reporting the functional states of tissues. SPECT imaging has been used as a diagnostic tool in several human disorders and can be used in animal models of diseases for physiopathological, genomic and drug discovery studies. However, most of the experimental models used in research involve rodents, which are at least one order of magnitude smaller in linear dimensions than man. Consequently, images of targets obtained with conventional gamma-cameras and collimators have poor spatial resolution and statistical quality. We review the methodological approaches developed in recent years in order to obtain images of small targets with good spatial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Small animal SPECT; Multipinhole collimators; Coded masks. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800001 |
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| Murta Jr.,L.O.; Ruiz,E.E.S.; Pazin-Filho,A.; Schmidt,A.; Almeida-Filho,O.C.; Simões,M.V.; Marin-Neto,J.A.; Maciel,B.C.. |
| The present study describes an auxiliary tool in the diagnosis of left ventricular (LV) segmental wall motion (WM) abnormalities based on color-coded echocardiographic WM images. An artificial neural network (ANN) was developed and validated for grading LV segmental WM using data from color kinesis (CK) images, a technique developed to display the timing and magnitude of global and regional WM in real time. We evaluated 21 normal subjects and 20 patients with LVWM abnormalities revealed by two-dimensional echocardiography. CK images were obtained in two sets of viewing planes. A method was developed to analyze CK images, providing quantitation of fractional area change in each of the 16 LV segments. Two experienced observers analyzed LVWM from... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Artificial neural network; Color kinesis images; Left ventricular function. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100001 |
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