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| Mukherjee,Debarati; Singh,Chingakham Brajakishor; Dey,Somaditya; Mandal,Supratim; Ghosh,Joydip; Mallick,Suvadip; Hussain,Aabid; Swapana,Ningombam; Ross,Samir Anis; Pal,Chiranjib. |
| Abstract In the present context of emergence of resistance aligned with the conventional anti-leishmanial drugs and occasional treatment failure compelled us to continue the search for replaceable therapeutic leads against Leishmaniainfection. Various ginger spices of the Zingiberaceae family are widely used as spices, flavouring agents, and medicines in Southeast Asia because of their unique flavour as well as due to their medicinal properties. Zerumbone, a natural component of Zingiber zerumbet (L.) Smith, has been studied for its pharmacological potential as antiulcer, antioxidant, anticancer, and antimicrobial. In this study, we have shown that zerumbone could induce ROS mediated apoptosis in Leishmania donovani promastigotes and also found effective... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leishmania donovani; Zingiber zerumbet; Zerumbone; Anti-leishmanial; ROS. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100048 |
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