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Determinants of HIV-1 mother-to-child transmission in Southern Brazil Anais da ABC (AABC)
Martínez,Ana M.B.; Hora,Vanusa P. da; Santos,Adriana L. dos; Mendoza-Sassi,Raul; Von Groll,Andréa; Soares,Esmeralda A.J.M.; D'Ávila,Nildo; Silveira,Jussara; Leal,Renata G.; Tanuri,Amilcar; Soares,Marcelo A..
Different human immunodeficiency virus type 1 (HIV-1) subtypes may have distinct biological, immunological and pathogenic properties. Efficiency of mother-to-child transmission (MTCT) may be among those properties, but few and controversial results have been described so far. In this study, 102 children born from HIV-1-infected mothers between 1998 and 2004 in the city of Rio Grande, Brazil were analyzed for potential risk factors associated with MTCT. That geographic region is characterized by a high proportion of subtype C-infected subjects, and it allowed comparison between subtypes B and C and their influence on MTCT. The analysis also included clinical, obstetric and immunological parameters. Multivariate regression analyses were conducted to evaluate...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; MTCT; Vertical transmission; Subtype C; Molecular epidemiology.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652006000100011
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