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| Silva,Mirna Luciano de Gois da; Fortes,Amanda Campos; Tomé,Adriana da Rocha; Silva Filho,Edson Cavalcanti da; Freitas,Rivelilson Mendes de; Soares-Sobrinho,José Lamartine; Leite,Cleide Maria da Silva; Soares,Mônica Felts de La Roca. |
| In view of growing interest in natural treatments, clays would appear to be a good alternative for speeding up the healing process during the treatment of wounds. Of the various clays, palygorskite, a clay from the Brazilian State of Piauí, composed of silicon and aluminum, has shown itself to be pharmaceutically useful as a healing agent. The aim of this article is to evaluate the effect on the healing of wounds of Piauí palygorskite, both in its natural state and when organophilic, by way of comparative analysis of macroscopic and histological tests on skin wounds in adult male and female two-month-old Wistar rats. To this end, a circular trichotomy of the dorsal cornus of the rats was carried out to confirm the effects of treatments involving 0.9%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Attapulgite/healing agent; Palygorskite/healing agent; Healing/experimental study; Skin wounds/healing; Skin wounds/experimental study. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400012 |
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| Viana,Osnir de Sá; Medeiros,Flávia Patrícia Morais; Grangeiro-Júnior,Severino; Albuquerque,Miracy Muniz; Soares,Mônica Felts La Roca; Soares-Sobrinho,José Lamartine; Alves,Lariza Darlene Santos; Rolim,Larissa Araújo; Silva,Keyla Emanuelle Ramos da; Rolim-Neto,Pedro José. |
| Efavirenz is a reverse transcriptase non analog nucleoside inhibitor used to treat HIV infections. A simple assay method by high performance liquid chromatography was developed and validated for efavirenz tablets. The physical chemical characteristics of efavirenz were investigated to developing the method. The method was validated observing the parameters described in USP 29. Analyses were performed by an ultraviolet detector at a 252 nm wavelength, on a reverse-phase column (C18, 250 mm x 3.9 mm, 10 μm), using an isocratic mobile phase containing acetonitrile/water/orthophosphoric acid (70:30:0.1). The validation parameters used were: selectivity, linearity, precision, accuracy, robustness, detection and quantification limits, and all resulting data were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Efavirenz/tablet assay; High performance liquid chromatography/quantitative analysis. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100012 |
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