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East1 toxin and its presence in a changing microbial world J. Venom. Anim. Toxins incl. Trop. Dis.
Sousa,C. P..
This review shows the structure, mode of action, and actual epidemiological data about EAST1 toxin. It is a particularly intriguing bacterial toxin that may subvert multiple cellular processes to yield intestinal epithelial cell secretion. EAST1 toxin was first described in strains of EAggEC that were associated with persistent diarrhea primarily in developing world countries. Molecular organization, mobility, and data in literature are suggesting that EAST1 could be a transposon. The insertion sequences in Escherichia coli and some of the usual transposition mechanisms as well as regulation are reviewed. This review emphasizes the presence of the gene astA in EPEC, EAggEC, A-EPEC, ETEC, DAEC, EIEC, and in non-diarrheagenic E. coli. It also discusses here...
Tipo: Info:eu-repo/semantics/article Palavras-chave: EAST1 toxin; AstA gene; Virulence in Escherichia coli; Virulence in Salmonella spp.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992003000100002
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Antagonistic properties of some microorganisms isolated from Brazilian tropical savannah plants against Staphylococcus coagulase-positive strain J. Venom. Anim. Toxins incl. Trop. Dis.
Ratti,R. P.; Serrano,N. F. G.; Hokka,C. O.; Sousa,C. P..
Endophytic microorganisms are relatively unstudied as potential sources of novel natural products for medical and commercial exploitation. The aim of this work was to investigate some Brazilian tropical savannah trees Cassia leptophylla and Prunus spp. in order to isolate the endophytic microorganisms associated with these plants. The samples were disinfected to eliminate the epiphytic population. Colonies were diluted and displayed as drops in media and growing colonies were inactivated. Staphylococcus coagulase-positive strain was used as indicator microorganism and subjected to the antibioses test. Data showed that the microorganisms isolated from Cassia leptophylla had no inhibition against Staphylococcus. On the other hand, microorganisms isolated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Endophytic microorganisms; Plants; Antibacterial activity; Bioactive compounds.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200007
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The versatile strategies of Escherichia coli pathotypes: a mini review J. Venom. Anim. Toxins incl. Trop. Dis.
Sousa,C. P..
The widespread species Escherichia coli includes a broad variety of different types, ranging from highly pathogenic strains to avirulent isolates. Few microorganisms are as versatile as E. coli. Pathogenic strains remain a leading cause of severe and persistent infant diarrhea in developing countries. They may be limited to colonization of a mucosal surface or can disseminate throughout the body and have been implicated in urinary tract infection, sepsis/meningitis and gastrointestinal infection. The human gastrointestinal tract is susceptible to diarrheagenic E. coli infections. Escherichia coli have effectively managed to subvert the host cytoskeleton for their own purposes causing substantial diarrheal disease, a major public health problem worldwide....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pathogenicity; Virulence; Escherichia coli pathotypes; Versatile strategies; Diarrheagenic E. coli categories; Public health.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300002
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