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| Santos,Edson N.; Lima,Joaquim C.S.; Noldin,Vânia F.; Cechinel-Filho,Valdir; Rao,Vietla S. N.; Lima,Evangelista F.; Schmeda-Hirschmann,Guillermo; Sousa Jr.,Paulo T.; Martins,Domingos T.O.. |
| Cariniana rubra Miers (Lecythidaceae), popularly known as "jequitibá-vermelho'', is a large Brazilian tree whose bark is used in infusion and decoction for the treatment of inflammatory conditions. This study aims to assess the anti-inflammatory, antinociceptive, and antipyretic effects of Cariniana rubra methanolic stem bark extract (EM Cr) using experimental animals. Anti-inflammatory activity of EM Cr was tested on carrageenan and dextran-induced rat paw edema, carrageenan-induced pleurisy in rats and acetic acid-increase vascular permeability in mice. Antinociceptive and antipyretic activities were evaluated using acetic acid-induced writhing, formalin and hot-plate tests in mice, as well as brewer's yeast-induced pyrexia in rats. The extract... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anti-inflammatory; Antinociceptive; Antipyretic; Cariniana rubra; Lecythidaceae; Triterpenoidal saponins. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000200015 |
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