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	Provedor de dados BJMBR (2) Autor Souza,S.J. de (2) Cerutti,J.M. (1) Oliveira,P.S.L. de (1) Osório,E.C. (1) Riggins,G.J. (1) Souza,J.E. de (1) Zaiats,A.C. (1) Mais... Palavra-chave Blast (1) Cancer (1) Fasta (1) Gene expression profiling (1) SAGE (1) Search engines (1) Serial analysis of gene expression (1) Tumor antigens (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2003 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última pp-Blast: a "pseudo-parallel" Blast BJMBR Osório,E.C.; Souza,J.E. de; Zaiats,A.C.; Oliveira,P.S.L. de; Souza,S.J. de. We have developed a software called pp-Blast that uses the publicly available Blast package and PVM (parallel virtual machine) to partition a multi-sequence query across a set of nodes with replicated or shared databases. Benchmark tests show that pp-Blast running in a cluster of 14 PCs outperformed conventional Blast running in large servers. In addition, using pp-Blast and the cluster we were able to map all human cDNAs onto the draft of the human genome in less than 6 days. We propose here that the cost/benefit ratio of pp-Blast makes it appropriate for large-scale sequence analysis. The source code and configuration files for pp-Blast are available at http://www.ludwig.org.br/biocomp/tools/pp-blast. Tipo: Info:eu-repo/semantics/other Palavras-chave: Blast; Search engines; Fasta. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400007 What can digital transcript profiling reveal about human cancers? BJMBR Cerutti,J.M.; Riggins,G.J.; Souza,S.J. de. Important biological and clinical features of malignancy are reflected in its transcript pattern. Recent advances in gene expression technology and informatics have provided a powerful new means to obtain and interpret these expression patterns. A comprehensive approach to expression profiling is serial analysis of gene expression (SAGE), which provides digital information on transcript levels. SAGE works by counting transcripts and storing these digital values electronically, providing absolute gene expression levels that make historical comparisons possible. SAGE produces a comprehensive profile of gene expression and can be used to search for candidate tumor markers or antigens in a limited number of samples. The Cancer Genome Anatomy Project has... Tipo: Info:eu-repo/semantics/article Palavras-chave: Serial analysis of gene expression; SAGE; Tumor antigens; Gene expression profiling; Cancer. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800003 Registros recuperados: 2 Primeira ... 1 ... Última

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