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| Caramelli,Bruno; Bernoche,Claudia Y.S.M. de; Sartori,Ana M. C.; Sposito,Andrei C.; Santos,Raul D.; Monachini,Maristela C.; Strabelli,Tania; Uip,Davi. |
| Hyperlipidemia has been frequently recorded as a side effect of treating HIV patients with protease inhibitors (PI). This study was initiated to analyze the modifications on blood lipids in HIV-patients receiving PI and the safety and efficacy of the treatment with fenofibrate. Total (TC) and HDL-cholesterol, triglycerides (TG), and CD4+ T-cell counts were measured in 30 HAART-naive patients (Group I) before and after PI introduction. In a second phase of the study, the effects of fenofibrate on lipids, CPK, CD4+, and viral load were determined in 13 patients (Group II) with elevated TC or TG. In Group I, 60% of the patients showed TC or TG elevations. Average increments of 31% and 146% in TC and TG respectively (p<0.0006 and p<0.0001) were observed.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cholesterol; Lipids; HIV infection; Triglycerides. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000600007 |
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