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Alignment of Linear Biochemical Pathways Using Protein Structural Classification Nature Precedings
Sridhar Hariharaputran; Thoralf Töpel; Timm Oberwahrenbrock; Ralf Hofestädt.
Metabolic, signaling and regulatory pathways form the basis of biological processes and are important for the analysis of cellular behavior and evolution. This paper presents an approach of aligning biochemical pathways on the basis of the structure of involved proteins and their classification. The suitable information is retrieved from an integrated database system.
SIGNALIGN is available at: http://agbi.techfak.uni-bielefeld.de/signalign/index.jsp 


Tipo: Manuscript Palavras-chave: Bioinformatics.
Ano: 2008 URL: http://precedings.nature.com/documents/1943/version/1
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BioSilicoSystems - A Multipronged Approach Towards Analysis and Representation of Biological Data (PhD Thesis) Nature Precedings
Sridhar Hariharaputran.
The rising field of integrative bioinformatics provides the vital methods to integrate, manage and also to analyze the diverse data and allows gaining new and deeper insights and a clear understanding of the intricate biological systems. The difficulty is not only to facilitate the study of heterogeneous data within the biological context, but it also more fundamental, how to represent and make the available knowledge accessible. Moreover, adding valuable information and functions that persuade the user to discover the interesting relations hidden within the data is, in itself, a great challenge. Also, the cumulative information can provide greater biological insight than is possible with individual information sources. Furthermore, the rapidly growing...
Tipo: Manuscript Palavras-chave: Bioinformatics.
Ano: 2010 URL: http://precedings.nature.com/documents/5164/version/1
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