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| Stark,Alan E.. |
| This paper gives a model of a structured population with respect to an autosomal locus with two alleles. The population reproduces in discrete and non-overlapping generations. The population is assumed to be in equilibrium in that exactly the same distribution of genotypic proportions is reproduced in each generation. The population is subdivided into 'localities' which are characterized by the local gene frequencies. Within each locality the genotypic proportions may depart from Hardy-Weinberg proportions and the same fixation index applies to all localities. The system departs from reality by assuming that the frequency of the first allele follows the beta distribution. However, this enables a convenient way to derive the mating frequencies of parents so... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Subdivided populations; F-statistics; Mating frequencies. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000100003 |
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| Stark,Alan E.. |
| This paper gives a general mating system for an autosomal locus with two alleles. The population reproduces in discrete and non-overlapping generations. The parental population, the same in both sexes, is arbitrary as is that of the offspring and the gene frequencies of the parents are maintained in the offspring. The system encompasses a number of special cases including the random mating model of Weinberg and Hardy. Thus it demonstrates, in the most general way possible, how genetic variation can be conserved in an indefinitely large population without invoking random mating or balancing selection. An important feature is that it provides a mating system which identifies when mating does and does not produce Hardy-Weinberg proportions among offspring. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hardy-Weinberg law; Non-random mating; General offspring distribution. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000400026 |
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| Stark,Alan E.. |
| The Hardy-Weinberg law has been used widely for about one hundred years with little question as to the foundations laid down by its originators. The basic assumption of random mating, that is choice of mates by a process akin to that of a lottery, was shown to produce genotypic proportions following the "binomial-square" rule, the so-called Hardy-Weinberg proportions (HWP). It has been assumed by many that random mating was the only way of pairing genes capable of producing HWP. However it has been shown that HWP can be obtained and maintained by non-random mating. The steps along the way to this revelation and some implications are reviewed. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hardy-Weinberg law; Non-random mating. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400001 |
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