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| Rungsa,Prapenpuksiri; Incamnoi,Paroonkorn; Sukprasert,Sophida; Uawonggul,Nunthawun; Klaynongsruang,Sompong; Daduang,Jureerut; Patramanon,Rina; Roytrakul,Sittiruk; Daduang,Sakda. |
| Abstract Background: Wasp venom is a complex mixture containing proteins, enzymes and small molecules, including some of the most dangerous allergens. The greater banded wasp (Vespa tropica) is well-known for its lethal venom, whose one of the major components is a hyaluronidase (HAase). It is believed that the high protein proportion and activity of this enzyme is responsible for the venom potency. Methods: In the present study, cDNA cloning, sequencing and 3D-structure of Vespa tropica venom HAase were described. Anti-native HAase antibody was used for neutralization assay. Results: Two isoforms, VesT2a and VesT2b, were classified as members of the glycosidase hydrolase 56 family with high similarity (42–97 %) to the allergen venom HAase. VesT2a gene... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Wasp venom; Vespa tropica; Hyaluronidase (HAase). |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100321 |
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| Srisong,Hathairat; Sukprasert,Sophida; Klaynongsruang,Sompong; Daduang,Jureerut; Daduang,Sakda. |
| Abstract Background: Fire ant venom is a complex mixture consisting of basic piperidine alkaloids, various biologically active peptides and protein components, including a variety of major allergenic proteins. Tropical fire ant Solenopsis geminata is an important stinging ant species that causes anaphylaxis and serious medical problems. Although the biological activities of allergenic venom proteins that are unique to ant venom, particularly Solenopsis 2 and 4, are still unknown, these proteins are believed to play important roles in mediating the effects of the piperidine derivatives in the venom. Methods: In the present study, the cDNA cloning, sequencing and three-dimensional structure of Sol g 4.1 venom protein are described. The recombinant Sol g... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fire ant; Sol g 4.1 protein; Allergen; Venom protein; Stinging ant. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100314 |
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