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Spot urine porphyrins/creatinine ratio profile of healthy Brazilian individuals adjusted for personal habits BJMBR
Alves,A.N.L.; Sumita,N.M.; Burattini,M.N.; Della Rosa,H.V..
Changes in urinary porphyrin excretion may be the result of hereditary causes and/or from environmental or occupational exposure. The objective of this study was to measure the amount of some porphyrins in spot urine samples obtained from volunteers randomly selected from a healthy adult population of São Paulo with a sensitive HPLC method and to estimate normal ranges for a non-exposed population. Spot urine samples were collected from 126 subjects (both genders, 18 to 65 years old) not occupationally exposed to porphyrinogenic agents. Porphyrin fractions were separated on RP-18 HPLC column eluted with a methanol/ammonium acetate buffer gradient, pH 4.0, and measured fluorometrically (excitation 405 nm/emission 620 nm). The amount of porphyrins was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Spot urine; Urinary porphyrins; Healthy population; Reference values.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800002
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