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	Provedor de dados Genet. Mol. Biol. (1) Autor Fu,Xiaoyan (1) Mei,Zhu (1) Sun,Lixin (1) Palavra-chave Association analysis (1) Autism (1) Genetic variants (1) RELN gene (1) Susceptibility (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2013 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Association between the g.296596G > A genetic variant of RELN gene and susceptibility to autism in a Chinese Han population Genet. Mol. Biol. Fu,Xiaoyan; Mei,Zhu; Sun,Lixin. Autism is a childhood neuro-developmental disorder, and Reelin (RELN) is an important candidate gene for influencing autism. This study aimed at investigating the influence of genetic variants of the RELN gene on autism susceptibility. In this study, 205 autism patients and 210 healthy controls were recruited and the genetic variants of the RELN gene were genotyped by the created restriction site-polymerase chain reaction (CRS-PCR) method. The influence of genetic variants on autism susceptibility was analyzed by association analysis, and the g.296596G > A genetic variant in exon10 of the RELN gene was detected. The frequencies of allele/genotype in autistic patients were significantly different from those in healthy controls, and a statistically... Tipo: Info:eu-repo/semantics/article Palavras-chave: Autism; Susceptibility; Association analysis; RELN gene; Genetic variants. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400003 Registros recuperados: 1 Primeira ... 1 ... Última

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