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| Takahachi,Gisele; Maluf,Márcia Luzia Ferrarezi; Svidzinski,Terezinha Inez Estivalet; Akimoto-Günther,Luciene Setsuko; Hübler,Márcia Rosangela Neves de Oliveira; Bersani-Amado,Ciomar Aparecida; Cuman,Roberto Kenji Nakamura. |
| The objective of this work was to evaluate biochemical parameters in Paracoccidioides brasiliensis infected mice and the effect of Canova medicine on these parameters. Mice infected with the isolate Paracoccidioides brasiliensis Pb18 and treated with Canova for 17 weeks were used. The biochemical parameters analysed were the levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and amylase, and the concentration of total proteins, albumin and globulins. The results suggested that the animals that were treated with Canova had less functional alterations in their internal organs. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Paracoccidioidomycosis; Biochemical profile; Canova; Paracoccidioides brasiliensis. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000700006 |
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| Shinobu,Cristiane Suemi; Ogatta,Sueli Fumie Yamada; Bizerra,Fenando; Furlaneto,Luciana; Peralta,Rosane Marina; Svidzinski,Terezinha Inez Estivalet; Consolaro,Marcia Edilaine Lopes. |
| The physiopathogenesis of vulvovaginal candidiasis (VVC) is still not completely elucidated. The objective of this study was to evaluate if there is a relationship between the different genotypes of Candida albicans, their main agent and the virulence of this yeast in vaginal isolates, and to check if there are laboratorial markers that can predict the ability of each isolate to develop VVC independently of symptoms. The production of exoenzymes protease, phospholipase and haemolysin, resistance to hydrogen peroxide, and the genotype were determined. Genotype A was predominant (75%), protease, phospholipase and haemolytic activity were highly expressed, and the majority of the yeasts were sensitive to H2O2 in 1 and 2 hours of exposure, suggesting that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: C. albicans; Vulvovaginal candidiasis; Genotype; Virulence factors. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300015 |
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| Taira,Cleison Ledesma; Mota,Valdeci Aparecido; Svidzinski,Terezinha Inez Estivalet. |
| Opportunistic fungi are those that normally would not cause diseases in otherwise healthy people, but are able to cause problems under some circumstances, and for this they need to possess a certain virulence potential. The objective of this study was to identify samples of filamentous fungi isolated from poultry barns in Cascavel, Paraná, and also to evaluate their virulence potential by assessing proteinase production, hemolytic activity, urease production, and growth rate at 37 ºC. We have evaluated the following samples: Acremonium hyalinulum (1 sample), Aspergillus sp. (12), Beauveria bassiana (1), Curvularia brachyspora (1), Paecilomyces variotti (1), and Penicillium sp. (2). Out of the 18 samples analyzed, 44.4% showed proteolytic activity using... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Filamentous fungi/identification; Filamentous fungi/virulence potential; Filamentous fungi/enzymatic activity; Filamentous fungi/hemolytic activity. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100019 |
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| Ferreira,Magda Rhayanny Assunção; Santiago,Rosilene Rodrigues; Silva-Rocha,Walicyranison Plínio; Souza,Luanda Barbara Ferreira Canário de; Faria,Maria Graciela Icher; Mello,João Carlos Palazzo de; Langassner,Silvana Maria Zucolotto; Chaves,Guilherme Maranhão; Milan,Eveline Pipolo; Svidzinski,Terezinha Inez Estivalet; Soares,Luiz Alberto Lira. |
| The aim of this study was evaluate the in vitro antifungal activity of crude extracts from Eugenia uniflora, Libidibia ferrea and Psidium guajava. The extracts were obtained by turbo-extraction using water (AQ) or acetone-water (AC-W) (7:3, v/v) as solvents and lyophilized to obtain the crude extracts (CE). The CE were characterized by UV-Vis, TLC and HPLC. The activity of CEs was investigated against clinical isolates of Candida spp. and the Minimum Inhibitory Concentration (MIC), MIC50 and MIC90 were determinated. The analysis by TLC showed that all CEs presented polyphenols (flavonoids and tannins). The CEs from E. uniflora showed higher amount of polyphenols (30.35 ± 2.15%, AC-W) and the HPLC analysis revealed the tannins in all extracts. The CEs of E.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal plants; Herbal extracts; Polyphenols; Candida isolates; Oral candidiasis. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100608 |
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| Leite,Gisela Myrian de Lima; Baeza,Lílian Cristiane; Ramos,Rosana Teixeira; Yamada,Sérgio Seiji; Magon,Thiago Ferreira dos Santos; Kimura,Elza; Svidzinski,Terezinha Inez Estivalet. |
| The use of central venous catheters (CVC) and broad-spectrum antibacterials are among the main risk factors for the development of candidemia in patients admitted to intensive care units (ICU). It is known that some antibacterials increase the resistance of these yeasts to azole antifungals. Thus, the aim of this research was to determine whether yeast present in CVC colonizations previously exposed to cell-wall targeted antibacterials benefit from a reduction in susceptibility to fluconazole and voriconazole, facilitating their ability to form biofilms. Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis and C. guilhermondii were seeded into antibacterial (cefepime, meropenem, vancomycin, and piperacillin-tazobactam) gradient plates produced in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Central venous cateter/use; Candidemia/control; Biofilm/formation; Antibacterials; Antifungals; Candida/species/control. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300467 |
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| Demarchi,Izabel Galhardo; Cardozo,Daniela Maira; Aristides,Sandra Mara Alessi; Moliterno,Ricardo Alberto; Silveira,Thaís Gomes Verzignassi; Cardoso,Rosilene Fressatti; Bertolini,Dennis Armando; Svidzinski,Terezinha Inez Estivalet; Teixeira,Jorge Juarez Vieira; Lonardoni,Maria Valdrinez Campana. |
| Highly active antiretroviral therapy (HAART) is used in patients infected with HIV. This treatment has been shown to significantly decrease opportunist infections such as those caused by viruses, fungi and particularly, protozoa. The use of HAART in HIV-positive persons is associated with immune reconstitution as well as decreased prevalence of oral candidiasis and candidal carriage. Antiretroviral therapy benefits patients who are co-infected by the human immunodeficiency virus (HIV), human herpes virus 8 (HHV-8), Epstein-Barr virus, hepatitis B virus (HBV), parvovirus B19 and cytomegalovirus (CMV). HAART has also led to a significant reduction in the incidence, and the modification of characteristics, of bacteremia by etiological agents such as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Highly active antiretroviral therapy; Antiretroviral drugs/activity; Opportunist infections/treatment. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100019 |
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