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| BISPO,VANDERSON S.; DANTAS,LUCAS S.; CHAVES FILHO,ADRIANO B.; PINTO,ISABELLA F.D.; SILVA,RAILMARA P. DA; OTSUKA,FELIPE A.M.; SANTOS,RODRIGO B.; SANTOS,ALINE C.; TRINDADE,DANIELLE J.; MATOS,HUMBERTO R.. |
| ABSTRACT Hepatic disorders such as steatosis and alcoholic steatohepatitis are common diseases that affect thousands of people around the globe. This study aims to identify the main phenol compounds using a new HPLC-ESI+-MS/MS method, to evaluate some oxidative stress parameters and the hepatoprotective action of green dwarf coconut water, caffeic and ascorbic acids on the liver and serum of rats treated with ethanol. The results showed five polyphenols in the lyophilized coconut water spiked with standards: chlorogenic acid (0.18 µM), caffeic acid (1.1 µM), methyl caffeate (0.03 µM), quercetin (0.08 µM) and ferulic acid (0.02 µM) isomers. In the animals, the activity of the serum γ-glutamyltranspeptidase (γ-GT) was reduced to 1.8 I.U/L in the coconut... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coconut water; Ethanol; Oxidative stress; Phenolic compounds. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301095 |
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