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| TSUZUKI, Nao; SEO, Jong-Pil; YAMADA, Kazutaka; HANEDA, Shingo; TABATA, Yasuhiko; SASAKI, Naoki; 羽田, 真悟; 佐々木, 直樹. |
| Platelet-rich plasma (PRP) was administered to cattle with hoof defects (10-mm drill hole) to promote sole defect healing. Two types of gels were prepared. One was a mixed gel [compound of gelatin microspheres (GM) incorporated with PRP and alginate] and was used for the test group, while the other was an alginate gel used for the control group. Each hole was filled with one of these gels. The drill hole depth, pressure pain, and hardness of the regenerated tissue were measured for 3 weeks after treatment. These measurements improved significantly in the test group than in the control group. The results suggest that a compound of GM incorporated with PRP and alginate had a hoof-regenerating effect in cattle. |
| Ano: 2012 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3889 |
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| SASAKI, Naoki; TSUZUKI, Nao; YAMADA, Michiaki; MINAMI, Takuto; YAMADA, Haruo; 佐々木, 直樹. |
| This study aimed to establish a standard dose and sample collection time for 13C phenylalanine and 13C-Dipeptide breath test in horses. To evaluate dose-dependent effects, healthy horses received 2.5 mg/kg, 5 mg/kg, and 10 mg/kg 13C phenylalanine dissolved in 1 ml/kg distilled water and 1.25 mg/kg, 2.5 mg/kg, and 5 mg/kg 13C dipeptide dissolved in 2 ml/kg distilled water. Tmax was observed during the sample collection time. For 13C phenylalanine, the standard deviation of Cmax at 5 mg/kg was lower than that of 10 mg/kg. For 13C dipeptide, the standard deviation of Tmax was the lowest at 5 mg/kg. This study revealed that an optimal dose for breath tests with 13C phenylalanine and 13C dipeptide may be 5 mg/kg in horses. |
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Palavras-chave: 13C-breath test; Dipeptide; Horses; Phenylalanine. |
| Ano: 2009 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3105 |
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