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Effects of isoflavone on oxidative stress parameters and homocysteine in postmenopausal women complaining of insomnia Biol. Res.
BRANDÃO,LETÍCIA C; HACHUL,HELENA; BITTENCOURT,LIA R; BARACAT,EDMUND C; TUFIK,SERGIO; D'ALMEIDA,VÂNIA.
Sleep disorders have an increased incidence after menopause. The objective of this work was to evaluate the effects of isoflavone on some oxidative stress markers in postmenopausal women complaining of insomnia. Women aged between 50-65 years (n=38) were recruited and assigned to a double-blind placebo controlled study for 4 months. The treated group received 100 mg/day of isoflavones. Blood collections were conducted on three different occasions to assess total glutathione; superoxide dismutase and catalase in erythrocytes; lipid peroxidation; and homocysteine plasma concentrations. No differences between the groups were observed. However, all the patients seem to improve their oxidative stress status and homocysteine concentration after treatment....
Tipo: Journal article Palavras-chave: Homocysteine; Isoflavones; Insomnia; Menopause; Oxidative stress.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300002
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