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Development and characterization of orally-disintegrating films for propolis delivery Ciênc. Tecnol. Aliment.
Borges,Josiane Gonçalves; Tagliamento,Marina; Silva,Aline Guerra; Sobral,Paulo José do Amaral; Carvalho,Rosemary Aparecida de.
This study aimed at evaluating the effect of different concentrations of hydrolyzed collagen (HC) on the properties of an orally disintegrating film containing propolis ethanol extract (PEE) as an active component. The films were evaluated in terms of total phenols, mechanical properties, solubility, contact angle, disintegration time, and microstructure. The films were prepared by casting with 2 g of protein mass (gelatin and HC), 30 g of sorbitol/100 g of protein mass, and 100 g of PEE/100 g of protein mass. HC was incorporated at concentrations of 0, 10, 20, and 30 g/100 g of protein mass. It was found that increased concentrations of HC reduced tensile strength and increased elongation; however, all films showed plastic behavior. An increase in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Protein; Natural bioactive compounds; Disintegration time.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612013000500005
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